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10/25/2006 Ten steps to master the art of peer review From Naturehttp://www.nature.com/naturejobs/2006/061019/full/nj7113-880b.html Ten steps to master the art of peer review. The peer-review process provides an opportunity for clinicians and scientists to train their fellows and postgraduate students as part of a one-on-one journal-club exercise. Supervisors can assess students' critical thinking and writing skills early in their careers. Consider these ten steps to teach the art of reviewing. 1) Explain how to proceed with a peer review, stressing the importance of respecting confidentiality and the rules of the journal or grant body. 2) Establish a submission deadline. The review process should take up to three hours. Set a time for final discussion before the deadline, allowing both student and supervisor time to read and review the work. 3) Adopt the right mindset. Don't accept the manuscript 'as is', and don't be hypercritical. The student might imagine that it's their own manuscript about to be rejected, and that they have the opportunity to improve it. 4) Read the manuscript once, taking rudimentary notes. 5) Follow the journal-specific author and reviewer instructions. Note those pertaining to the category of the manuscript, the word length, abstract structure and the format for references, figures and tables. 6) Verify each citation with PubMed or similar — which also gives you a chance to read generally on the topic. Highlighting minor citation errors shows that the paper has been read thoroughly. Ask the following: does the submitted work complement or duplicate the authors' and others' previous work? 7) Re-read the manuscript armed with the specific author instructions and good background knowledge. 8) Write the review envisaging that the editor is too busy to read the manuscript in-depth. Summarize the key features in a paragraph, stating the topic of the paper, what was performed, the key conclusions drawn, why this is important, and why this is a novel contribution. Strengths or problems with the manuscript or methodology should then be detailed. 9) Write all comments as if they will be seen by the authors. Although most reviewers are anonymous, caution students that a disgruntled author could recognize one's spelling variances, grammar or clichés. 10) Submit the review, telling the editor the review was written with a student and that you agree with their assessment. Show the student the submitted review as well as the editor's and other reviewers' comments. 8/19/2006 Skatinghttp://inlineskating.about.com/od/masteringthebasics/a/beginners1.htm
n年前本科时曾学过一学期的轮滑，可惜那时候没钱买双像样的旱冰鞋。上课用的是一双借的滑不起来的鞋，一个学期下来也没有学到多少东西。前几天去路过SportsAuthority看见溜冰鞋，忽然心血来潮想滑冰了。了解了鞋基本东西，前天看见SportsAuthority有了25％ off的胖子，于是决定马上买鞋子了。选择不多，只有一双inline stake(Rollerblade Zetrablade)觉得还好看, 昨天下班回家路上就把它买了。 昨天去朋友家玩，回家已经晚上1点多了。但是按捺不住试试鞋子的冲动，就穿上鞋子去马路上滑了。感觉还不错，虽然一开始有点重心不稳，但也没有摔。过了几分钟也有点适应了， 找到了点感觉。身子在轮子上慢慢滑行，自己仿佛年轻了些。呵呵。明天就可以去公园和朋友一起滑了，希望能从他们那学点。对了，还的去买些护腕，护肘等东西。 从现在开始，慢慢找回好动的自己。 8/14/2006 Silent running: the race to the clinicSilent running: the race to the clinicA technique for turning genes off has sparked a flurry of biotech investment. Erika Check investigates.Nature 442, 614-615(10 August 2006) | doi:10.1038/442614a; Published online 9 August 2006 Silence is golden — at least, that's what two US biotechnology companies are hoping. They aim to reap the rewards of bringing a method for silencing genes into the clinic, where they claim it could lead to treatments for everything from viral diseases to cancer. The technique, known as RNA interference or RNAi, could offer a safe and effective way of turning off a gene. And, although it is early days, many see it as a likely moneyspinner for the biotechnology industry. "It is a while away from being an impactful sector," says Sapna Srivastava, an analyst at Morgan Stanley in New York. "But it has the potential to be really big." Two well-funded companies are leading the way for now: Alnylam Pharmaceuticals of Cambridge, Massachusetts, and Sirna Therapeutics of Boulder, Colorado. These two firms are jousting over intellectual-property rights, and each has been forging corporate alliances in a bid to capitalize on RNAi's potential. 8/13/2006 Oversea Fish Tank想养鱼很久了，可是一直拖着，或是忘了或是没时间，或是想等个鱼缸deal，或是怕麻烦。鱼缸的名字也是早就想好了的，叫做‘Oversea’，不知道确切的中文名应该叫什么， ‘海外游鱼‘，’海外水鱼‘，，‘四海之鱼’。鱼缸中的鱼名呢，当年的想法是用在Oversea认识的ID命名，给记忆增加点内容。当然在鱼缸中的ID是要得到ID本人的许可的。 如果没有ID同意，那就只好以自己的ID命名，然后变几个花样，名字总会叫起来的。 去Petco，PetSmart看过几次，差不到也知道要买个啥样的了，本来还想再看看的。 但是今天忽然心血来潮，于是决定今天就买了。直接驱车去Petco，买了个29加仑的Kit，包括glass fish tank，filter, heater, hood light, thermometer, 119刀，还可以忍受。回家安装的时候发现没有石头和水草，就又回去先买了15磅石头，两根水草，20刀。按照上面的指示按照完毕，先测验鱼缸。感觉还可以。 等鱼缸稳定后（大约一两个星期）就可以慢慢买鱼和其它的装饰品了。 鱼名的征集从今天就开始了, 可以直接在这里留名，或者联系prospect。
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